Hub City Times

Top Menu

  • Contact Us
  • E-Editions
  • Subscribe

Main Menu

  • News
    • Around the County
    • Arts & Ent
    • Education
    • Government
    • Local
  • Covid 19
  • Opinion
  • Sports
    • Sports News
    • High School Sports Scores
    • Wisconsin Rapids Rafters
  • Coming Events
  • Business
  • Obits
  • Classifieds
    • Place Ad
    • View Ads
  • Legal Ads
    • Our Legals
    • Statewide
  • Senior Photos 2021
  • Contact Us
  • E-Editions
  • Subscribe

logo

Hub City Times

  • News
    • Around the County
    • Arts & Ent
    • Education
    • Government
    • Local
  • Covid 19
  • Opinion
  • Sports
    • Sports News
    • High School Sports Scores
    • Wisconsin Rapids Rafters
  • Coming Events
  • Business
  • Obits
  • Classifieds
    • Place Ad
    • View Ads
  • Legal Ads
    • Our Legals
    • Statewide
  • Senior Photos 2021
FeaturedHealth
Home›Featured›Marshfield Clinic genomic research helps build case for president’s Precision Medicine Initiative

Marshfield Clinic genomic research helps build case for president’s Precision Medicine Initiative

By Hub City Times
February 3, 2015
1138
0
Share:
Marshfield Clinic

MARSHFIELD — Marshfield Clinic’s effort over the past decade included the development of a database that allows

Brilliant

Brilliant

providers to tailor health care to an individual’s precise genetic profile. This approach was an integral part in President Barack Obama’s new Precision Medicine Initiative.

Murray Brilliant, Ph.D., director for Marshfield Clinic’s Center for Human Genetics, was a guest at last Friday’s White House announcement where the president shared how this bold, new research effort will revolutionize how to improve health and treat disease. Obama first announced the initiative in his State of the Union address.

Precision medicine is an innovative approach to disease prevention and treatment that takes into account individual

differences in people’s genes, environments, and lifestyles. It gives clinicians tools to better understand complex mechanisms underlying a patient’s health, disease, or condition and to better predict which treatments will be most effective.

The Precision Medicine Initiative objectives include:

—Accelerating biomedical discoveries.

—Investing in the design and testing of effective, tailored treatments for cancer.

—Creation of a voluntary national research cohort of 1 million people.

Brilliant oversees Marshfield Clinic’s Personalized Medicine Research Project (PMRP). Created in 2001, PMRP now has a database of more than 20,000 volunteers. PMRP is one of the largest population-based genetic research projects in the U.S.

Marshfield Clinic now uses information gained from years of PMRP studies to predict which patients will have adverse reactions to commonly prescribed anticoagulant and cholesterol-lowering medications based on their genetic makeup and medical history.

“PMRP was designed to understand genetic underpinnings of disease, and we have now developed one of the first programs that demonstrated precision medicine works and is effective,” Brilliant said. “This method was researched, and a pilot project … is now in the implementation phase. We demonstrated this works in small groups and believe we are able to generalize this for all of our patients.”

One way patients benefited from the new implementation of precision medicine was through a study of genetic variation in genes associated with drug reactions.

Based on their medical records, patients who were likely to go on certain commonly prescribed anticoagulant and cholesterol-lowering medications were first tested for how they are likely to respond to the medication. Patients who are at risk for a bad reaction have an alert in their electronic health record that notifies their provider about a possible adverse reaction when a prescription for that drug is written, and then an alternative therapy is recommended.

“We can look at their genetic variations but also their clinical conditions and outcomes of care to develop precise, almost fingerprint-like uniqueness medical care for each individual based on genetic and other risk factors,” Brilliant said. “Employing precision medicine can insure that our patients get better health care with fewer bad outcomes.”

TagsFeaturedgeneticshealthmarshfield clinicscience
Previous Article

The city speaks: Do your part

Next Article

First-place Waupaca nets win over Marshfield girls ...

0
Shares
  • 0
  • +
  • 0
  • 0
  • 0
  • 0

Related articles More from author

  • LocalNews

    Marshfield man struck by train

    July 30, 2014
    By Hub City Times
  • Photo Gallery

    Photos from Relay For Life in Marshfield

    August 2, 2014
    By HubCityAdmin
  • News

    Cancer gets lapped at Relay For Life

    August 2, 2014
    By Hub City Times
  • Business

    Hotel Marshfield combines sophistication with comfort

    August 6, 2014
    By Hub City Times
  • Arts & Entertainment

    New Visions Gallery fundraises in style

    August 8, 2014
    By Hub City Times
  • BusinessFood

    Marshfield Farmers’ Market in full bloom

    August 9, 2014
    By Hub City Times

Leave a reply Cancel reply

You must be logged in to post a comment.

About Us


Hub City Times is published by Multi Media Channels LLC, N2919 County Road QQ Waupaca, WI 54981.

Copyright © 2020 Multi Media Channels, All Rights Reserved. Designed by MMC Team Awesome
×